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A Literature Based Method for Identifying Gene-Disease Connections Lada A. Adamic, Dennis Wilkinson, Bernardo A. Huberman, Eytan Adar We present a statistical method that can swiftly identify, from the literature, sets of genes known to be associated with given diseases. It offers a comprehensive way to treat alias symbols, a statistical method for computing the relevance of the gene to the query, and a novel way to disambiguate gene symbols from other abbreviations. The method is illustrated by finding genes related to breast cancer. IEEE Computer Society Bioinformatics Conference, August, 2002. Available in pre-print form at: PDF (90kb) Supplementary information at: http://www.hpl.hp.com/shl/papers/genelit/sup.html |